ABSTRACT
Objective:To compare influence of percutaneous coronary intervention(PCI)and thrombolytic therapy on therapeutic effect and reperfusion in patients with acute myocardial infarction(AMI).Methods:A total of 118 AMI patients treated in our hospital from Jan 2013 to Dec 2016 were enrolled.They were divided into thrombolysis group (n=38)and PCI group(n=80).Therapeutic effect,cardiac function and reperfusion indexes were compared be-tween two groups.Results:Compared with thrombolysis group,there was significant rise in total effective rate (84.21% vs.97.50%),and significant reduction in total incidence rate of adverse events(18.42% vs.2.50%)in PCI group,P< 0.01 both.Compared with before treatment,there were significant reductions in left ventricular end-systolic dimension(LVESd)of two groups and left ventricular end-diastolic dimension(LVEDd)of PCI group, and significant rise in creatine kinase isoenzyme-MB(CK-MB)level of two groups after treatment,P=0.001 all. Compared with thrombolysis group after treatment,there were significant reductions in LVEDd[(32.45 ± 2.21)mm vs.(29.86 ± 3.96)mm]and LVESd[(49.85 ± 1.32)mm vs.(46.86 ± 2.34)mm],and significant rise in CK-MB level[(389.74 ± 2.74)ng/ml vs.(706.96 ± 3.78)ng/ml]in PCI group,P=0.001 all.Conclusion:Compared with thrombolytic therapy,PCI possesses more significant therapeutic effect on AMI.It can more significantly im-prove patient′s cardiac function,and rise CK-MB level,which has better clinical value.